SRI2022 is the second meeting in the annual SRI series that unites global leaders, experts, industry, and innovators to inspire action and promote transformation in sustainability. SRI2022 offers a platform for meaningful solutions to society, transformations at the intersection of research and innovation, and collaborations for change on the ground. A joint initiative of Future Earth and the Belmont Forum, the SRI Congress is a space of dedicated advocacy for sustainability scholarship and innovation, transdisciplinary and cross-sectoral collaboration and action. An important objective of SRI2022 is to amplify the voice of sustainability science and innovation in the Global South, specifically for the African continent, through raising awareness and propelling discussions about sustainable priorities for Africa.